Histone H3 polyclonal, anti-human

Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Synonyms: HIST3H3；H3.4；H3/g；H3FT；H3t；histone H3.1t

Cellular Location: Nucleus

Immunogen:
A synthetic peptide of human Histone H3

Gene Symbol: Histone H3

Gene ID: 8350/8351/8352/8353/8354/8355/8356/8357/8358/8968

Swiss prot: P68431

Calculated MW: 15kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-300,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.