Histone H4 (Acetyl-K16) polyclonal, anti-human, mouse
€428.00
In stock
SKU
BS74024
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Alternative Name:
FO108, H4, H4/n, H4F2, H4FN, HIST2H4
Application Dilution: WB: 1:500 - 1:2000
Specificity: Histone H4 (Acetyl-K16) polyclonal antibody detects endogenous levels of Histone H4 protein only when acetylated at K16.
Immunogen:
A synthetic acetylated peptide corresponding to residues surrounding Lysine 16 of human Histone H4
MW: ~ 13 kDa
Swis Prot.: P62805
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Alternative Name:
FO108, H4, H4/n, H4F2, H4FN, HIST2H4
Application Dilution: WB: 1:500 - 1:2000
Specificity: Histone H4 (Acetyl-K16) polyclonal antibody detects endogenous levels of Histone H4 protein only when acetylated at K16.
Immunogen:
A synthetic acetylated peptide corresponding to residues surrounding Lysine 16 of human Histone H4
MW: ~ 13 kDa
Swis Prot.: P62805
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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