HK1/HK2 polyclonal, anti-human, mouse, rat

Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Synonyms: HK, HKD, HKI, HXK1, RP79, HMSNR, HK1-ta, HK1-tb, HK1-tc, hexokinase, HKII, HXK2

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human HK1/HK2

Gene Symbol: HK1/HK2

Gene ID: 3098/3099

Swiss prot: P19367/P52789

Calculated MW: 102kDa

Recommended dilution:
WB 1:1000-5000, IHC 1:100-300,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.