HK1 Polyclonal Antibody

Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
BB404130, Brain form hexokinase, dea, DrHXK1, EC 2.7.1.1, Glycolytic enzyme, HEXOKIN, hexokinase I, Hexokinase PI, Hexokinase type I, Hexokinase, tumor isozyme, Hexokinase-1, Hexokinase-A, HK I, HK1, HK1 tb, Hk1-s, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, HXK1, im:7148527, mHk1-s, wu:fc09d08, wu:fc16e02, wu:fc21e02, wu:fq14b11, zgc:55790, zgc:77618

Immunogen: Recombinant protein of human HK1

Swissprot: P19367
Gene Accession: BC008730

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6517/sc-6518/sc-28885