HK2 Polyclonal Antibody

Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
DKFZp686M1669, Hexokinase 2, Hexokinase 2 muscle, Hexokinase type II, Hexokinase-2, HK 2, HK II, HK2, HKII, HxK 2, HxK2, HXK2, Muscle form hexokinase

Immunogen: Recombinant protein of human HK2

Swissprot: P52789
Gene Accession: BC021116

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6521/sc-6522/sc-28889

Citation(s):
https://www.sciencedirect.com/science/article/pii/S1349007918300835