HKDC1 polyclonal, anti-human, mouse, rat

Background:
As the recently identified fifth isoform of hexokinase, HKDC1 catalyzes the rate-limiting and first obligatory step of glucose metabolism, which is the ATP-dependent phosphorylation of glucose to G6P. Though its particular biological function remains unclear, HKDC1 has been suggested to play a more major role in glucose metabolism during pregnancy, as the mother would need to provide enough energy for both herself and the fetus. HKDC1 is ubiquitously expressed, with the highest levels of expression in pharynx, thymus, colon, esophagus, and eye tissue.

Alternative Name:
HKDC1, BC016235, Hexokinase domain containing 1, Hexokinase domain-containing protein 1, Hkdc1, HKDC1, Putative hexokinase HKDC1,

Application Dilution:
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: HKDC1 polyclonal antibody detects endogenous levels of HKDC1 protein.

Immunogen:
Recombinant protein within human HKDC1 260-460aa.

MW: 82/90/102 kDa

Swiss-Prot: Q2TB90(Human) Q91W97(Mouse)

Purification & Purity:
Protein affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.