HKLK3 monoclonal (C234), anti-human
€470.00
In stock
SKU
AC-AM2088a
Catalog Number: AC-AM2088a
Size: 100 µl
Isotype: mouse IgM
Clone Name: 551CT16.3.5
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgM
Clone Name: 551CT16.3.5
Applications: WB
Datasheet
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Background:
Kallikreins are a subgroup of serine proteases havingdiverse physiological functions. Growing evidence suggests thatmany kallikreins are implicated in carcinogenesis and some havepotential as novel cancer and other disease biomarkers. This geneis one of the fifteen kallikrein subfamily members located in acluster on chromosome 19. Its protein product is a protease presentin seminal plasma. It is thought to function normally in theliquefaction of seminal coagulum, presumably by hydrolysis of thehigh molecular mass seminal vesicle protein. Serum level of thisprotein, called PSA in the clinical setting, is useful in thediagnosis and monitoring of prostatic carcinoma. Alternate splicingof this gene generates several transcript variants encodingdifferent isoforms.
Other Names:
Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS
Target/Specificity:
This HKLK3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from human HKLK3.
Antigen Region:
220-250
Antigen Type: Synthetic Peptide
Gene Name: KLK3
Gene ID: 354
Primary Accession: P07288
NCBI Accession: NP_001025218.1;NP_001025219.1;NP_001639.1
Other Accession: NP_001025218.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Kallikreins are a subgroup of serine proteases havingdiverse physiological functions. Growing evidence suggests thatmany kallikreins are implicated in carcinogenesis and some havepotential as novel cancer and other disease biomarkers. This geneis one of the fifteen kallikrein subfamily members located in acluster on chromosome 19. Its protein product is a protease presentin seminal plasma. It is thought to function normally in theliquefaction of seminal coagulum, presumably by hydrolysis of thehigh molecular mass seminal vesicle protein. Serum level of thisprotein, called PSA in the clinical setting, is useful in thediagnosis and monitoring of prostatic carcinoma. Alternate splicingof this gene generates several transcript variants encodingdifferent isoforms.
Other Names:
Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS
Target/Specificity:
This HKLK3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from human HKLK3.
Antigen Region:
220-250
Antigen Type: Synthetic Peptide
Gene Name: KLK3
Gene ID: 354
Primary Accession: P07288
NCBI Accession: NP_001025218.1;NP_001025219.1;NP_001639.1
Other Accession: NP_001025218.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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