HLA A polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
HLA-A, namely HLA A, is a group of human leukocyte antigens (HLA) that are coded for by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is simply the major histocompatibility complex (MHC) specific to humans. HLA-A is one of three major types of human MHC class I cell surface receptors. The others are HLA-B and HLA-C. And it is critical to the cytotoxic t-cell controlled immune response to viruses and other intracellular pathogens. Because each HLA-A gene has a high affinity for slightly different peptides, certain HLA-As are associated with increased risk, more rapid progression, and/or increased severity of many diseases. For similar reasons, HLA-A matching is essential to successful tissue transplants.

Description:
Rabbit IgG polyclonal antibody for HLA class I histocompatibility antigen, A-2 alpha chain (HLA-A) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
A 28 antibody, A 9 antibody, Antigen presenting molecule antibody, Aw 24 antibody, Aw 68 antibody, CLASS I HISTOCOMPATIBILITY ANTIGEN antibody, H2 K1 antibody, H2K antibody, HLA A antibody, HLA class I histocompatibility antigen A 1 alpha chain antibody, HLA class I histocompatibility antigen A 11 alpha chain antibody, HLA class I histocompatibility antigen A 2 alpha chain antibody, HLA class I histocompatibility antigen A 24 alpha chain antibody, HLA class I histocompatibility antigen A 3 alpha chain antibody, HLA class I histocompatibility antigen A 30 alpha chain antibody, HLA class I histocompatibility antigen A 32 alpha chain antibody, HLA class I histocompatibility antigen A 68 alpha chain antibody, HLA class I histocompatibility antigen, A 1 alpha chain antibody, HLAA antibody, Leukocyte antigen class I A antibody, Major histocompatibility complex class I A antibody, Major histocompatibility complex, class I, A antibody, MHC class I antigen A 1 antibody, MHC class I antigen A*11 antibody, MHC class I antigen A*2 antibody, MHC class I antigen A*24 antibody, MHC class I antigen A*3 antibody, MHC class I antigen A*30 antibody, MHC class I antigen A*32 antibody, MHC class I antigen A*68 antibody, MHC class I antigen HLA A heavy chain antibody, MHC class I heavy chain H2 K antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human HLA A (82-106aa EYWDGETRKVKAHSQTHRVDLGTLR).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.