HLA-ABC (MHC I) (clone 246-B8.E7), anti-human, mouse, non-human primates

HLA-ABC (MHC I) (clone 246-B8.E7), anti-human, mouse, non-human primates

€0.00
In stock
SKU
ARP-24-3105-MSM1
Catalog Number: 24-3105-MSM1
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG2a, kappa
Decription:
Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Synonyms: HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A + B + C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC

Clone: 246-B8.E7

Isotype: Mouse IgG2a, kappa

Immunogen: Human peripheral blood leukocytes

Reactivity: human, mouse and non-human primates. Others not known.

Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (0.5-1ug/ml)
Optimal dilution for a specific application should be determined.

Reactivity: THP-1 and Jurkat cells. Tonsil or lymph node.

Concentration: 0.2mg/ml

Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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