HLA-DPA1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP17796b
Background:
HLA-DPA1 belongs to the HLA class II alpha chainparalogues. This class II molecule is a heterodimer consisting ofan alpha (DPA) and a beta (DPB) chain, both anchored in themembrane. It plays a central role in the immune system bypresenting peptides derived from extracellular proteins. Class IImolecules are expressed in antigen presenting cells (APC: Blymphocytes, dendritic cells, macrophages). The alpha chain isapproximately 33-35 kDa and its gene contains 5 exons. Exon oneencodes the leader peptide, exons 2 and 3 encode the twoextracellular domains, exon 4 encodes the transmembrane domain andthe cytoplasmic tail. Within the DP molecule both the alpha chainand the beta chain contain the polymorphisms specifying the peptidebinding specificities, resulting in up to 4 different molecules.
Other Names:
HLA class II histocompatibility antigen, DP alpha 1 chain, DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1, HLA-DPA1, HLA-DP1A, HLASB
Gene Name: HLA-DPA1
Gene ID: 3113
Primary Accession: P20036
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
HLA-DPA1 belongs to the HLA class II alpha chainparalogues. This class II molecule is a heterodimer consisting ofan alpha (DPA) and a beta (DPB) chain, both anchored in themembrane. It plays a central role in the immune system bypresenting peptides derived from extracellular proteins. Class IImolecules are expressed in antigen presenting cells (APC: Blymphocytes, dendritic cells, macrophages). The alpha chain isapproximately 33-35 kDa and its gene contains 5 exons. Exon oneencodes the leader peptide, exons 2 and 3 encode the twoextracellular domains, exon 4 encodes the transmembrane domain andthe cytoplasmic tail. Within the DP molecule both the alpha chainand the beta chain contain the polymorphisms specifying the peptidebinding specificities, resulting in up to 4 different molecules.
Other Names:
HLA class II histocompatibility antigen, DP alpha 1 chain, DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1, HLA-DPA1, HLA-DP1A, HLASB
Gene Name: HLA-DPA1
Gene ID: 3113
Primary Accession: P20036
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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