HLA-DPA1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP17796b
Catalog Number: AC-AP17796b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36729
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36729
Applications: WB
Datasheet
Request Information
Background:
HLA-DPA1 belongs to the HLA class II alpha chainparalogues. This class II molecule is a heterodimer consisting ofan alpha (DPA) and a beta (DPB) chain, both anchored in themembrane. It plays a central role in the immune system bypresenting peptides derived from extracellular proteins. Class IImolecules are expressed in antigen presenting cells (APC: Blymphocytes, dendritic cells, macrophages). The alpha chain isapproximately 33-35 kDa and its gene contains 5 exons. Exon oneencodes the leader peptide, exons 2 and 3 encode the twoextracellular domains, exon 4 encodes the transmembrane domain andthe cytoplasmic tail. Within the DP molecule both the alpha chainand the beta chain contain the polymorphisms specifying the peptidebinding specificities, resulting in up to 4 different molecules.
Other Names:
HLA class II histocompatibility antigen, DP alpha 1 chain, DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1, HLA-DPA1, HLA-DP1A, HLASB
Target/Specificity:
This HLA-DPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-259 amino acids from the C-terminal region of human HLA-DPA1.
Antigen Region:
231-259
Antigen Type: Synthetic Peptide
Gene Name: HLA-DPA1
Gene ID: 3113
Primary Accession: P20036
NCBI Accession: NP_001229453.1;NP_001229454.1;NP_291032.2
Other Accession: NP_291032.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
HLA-DPA1 belongs to the HLA class II alpha chainparalogues. This class II molecule is a heterodimer consisting ofan alpha (DPA) and a beta (DPB) chain, both anchored in themembrane. It plays a central role in the immune system bypresenting peptides derived from extracellular proteins. Class IImolecules are expressed in antigen presenting cells (APC: Blymphocytes, dendritic cells, macrophages). The alpha chain isapproximately 33-35 kDa and its gene contains 5 exons. Exon oneencodes the leader peptide, exons 2 and 3 encode the twoextracellular domains, exon 4 encodes the transmembrane domain andthe cytoplasmic tail. Within the DP molecule both the alpha chainand the beta chain contain the polymorphisms specifying the peptidebinding specificities, resulting in up to 4 different molecules.
Other Names:
HLA class II histocompatibility antigen, DP alpha 1 chain, DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1, HLA-DPA1, HLA-DP1A, HLASB
Target/Specificity:
This HLA-DPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-259 amino acids from the C-terminal region of human HLA-DPA1.
Antigen Region:
231-259
Antigen Type: Synthetic Peptide
Gene Name: HLA-DPA1
Gene ID: 3113
Primary Accession: P20036
NCBI Accession: NP_001229453.1;NP_001229454.1;NP_291032.2
Other Accession: NP_291032.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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