HLA-DPB1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP13834c
Catalog Number: AC-AP13834c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33626
Applications: WB, FC, IHC-P-Leica
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33626
Applications: WB, FC, IHC-P-Leica
Datasheet
Request Information
Background:
HLA-DPB belongs to the HLA class II beta chain paralogues.This class II molecule is a heterodimer consisting of an alpha(DPA) and a beta chain (DPB), both anchored in the membrane. Itplays a central role in the immune system by presenting peptidesderived from extracellular proteins. Class II molecules areexpressed in antigen presenting cells (APC: B lymphocytes,dendritic cells, macrophages). The beta chain is approximately26-28 kDa and its gene contains 6 exons. Exon one encodes theleader peptide, exons 2 and 3 encode the two extracellular domains,exon 4 encodes the transmembrane domain and exon 5 encodes thecytoplasmic tail. Within the DP molecule both the alpha chain andthe beta chain contain the polymorphisms specifying the peptidebinding specificities, resulting in up to 4 different molecules.
Other Names:
HLA class II histocompatibility antigen, DP beta 1 chain, HLA class II histocompatibility antigen, DP(W4) beta chain, MHC class II antigen DPB1, HLA-DPB1, HLA-DP1B
Target/Specificity:
This HLA-DPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the Central region of human HLA-DPB1.
Antigen Region:
77-105
Antigen Type: Synthetic Peptide
Gene Name: HLA-DPB1
Gene ID: 3115
Primary Accession: P04440
NCBI Accession: NP_002112.3
Other Accession: NP_002112.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
HLA-DPB belongs to the HLA class II beta chain paralogues.This class II molecule is a heterodimer consisting of an alpha(DPA) and a beta chain (DPB), both anchored in the membrane. Itplays a central role in the immune system by presenting peptidesderived from extracellular proteins. Class II molecules areexpressed in antigen presenting cells (APC: B lymphocytes,dendritic cells, macrophages). The beta chain is approximately26-28 kDa and its gene contains 6 exons. Exon one encodes theleader peptide, exons 2 and 3 encode the two extracellular domains,exon 4 encodes the transmembrane domain and exon 5 encodes thecytoplasmic tail. Within the DP molecule both the alpha chain andthe beta chain contain the polymorphisms specifying the peptidebinding specificities, resulting in up to 4 different molecules.
Other Names:
HLA class II histocompatibility antigen, DP beta 1 chain, HLA class II histocompatibility antigen, DP(W4) beta chain, MHC class II antigen DPB1, HLA-DPB1, HLA-DP1B
Target/Specificity:
This HLA-DPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the Central region of human HLA-DPB1.
Antigen Region:
77-105
Antigen Type: Synthetic Peptide
Gene Name: HLA-DPB1
Gene ID: 3115
Primary Accession: P04440
NCBI Accession: NP_002112.3
Other Accession: NP_002112.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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