HLA-DQ (clone HI118) FITC, anti-human
€435.00
In stock
SKU
251041
Protein Family: Cellular Antigens
Pathway and Disease: Immune System
Description:
The HLA-DQ (HI118) antibody recognizes the HLA DQ antigen, a HLA class II antigen that is mainly expressed on specialized antigen-presenting cells (APC), dendritic cells, B-cells, monocytes, macrophages and activated T-cells. HLA class II antigens present exogenous-derived antigens to T-cell receptors (TCR) on CD4+ T lymphocytes. Both chains in HLA DQ are polymorphic. HLA DQ is highly expressed in the thymic cortex and is expressed after DR and DP during hematopoietic progenitor cell development. This antibody recognizes DQ6 and DQ8 but not DQ2.
Alternate Names: HLA class II histocompatibility antigen, DQ
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Knapp W., et al., eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York
Pathway and Disease: Immune System
Description:
The HLA-DQ (HI118) antibody recognizes the HLA DQ antigen, a HLA class II antigen that is mainly expressed on specialized antigen-presenting cells (APC), dendritic cells, B-cells, monocytes, macrophages and activated T-cells. HLA class II antigens present exogenous-derived antigens to T-cell receptors (TCR) on CD4+ T lymphocytes. Both chains in HLA DQ are polymorphic. HLA DQ is highly expressed in the thymic cortex and is expressed after DR and DP during hematopoietic progenitor cell development. This antibody recognizes DQ6 and DQ8 but not DQ2.
Alternate Names: HLA class II histocompatibility antigen, DQ
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Knapp W., et al., eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York
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