HLA-DRB1 polyclonal (N-term), anti-human

HLA-DRB1 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP6885a
Catalog Number: AC-AP6885a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21019
Applications: WB, IHC-P, FC
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Background:
HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons.

Other Names:
HLA class II histocompatibility antigen, DRB1-1 beta chain, MHC class II antigen DRB1*1, DR-1, DR1, HLA-DRB1

Target/Specificity:
This HLA-D_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids of human HLA-D_1.

Antigen Region:
30-58

Antigen Type: Synthetic Peptide
Primary Accession: P04229
Other Accession: Q30167
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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