HORMAD1 polyclonal, anti-human
€470.00
In stock
SKU
AC-AP70390
Background:
Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
Other Names:
HORMAD1; NOHMA; HORMA domain-containing protein 1; Cancer/testis antigen 46; CT46; Newborn ovary HORMA protein
Antigen Type: synthetic peptide
Antigen Type: HORMAD1 (HGNC:25245)
Gene ID: 84072
Primary Accession: Q86X24
Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
Other Names:
HORMAD1; NOHMA; HORMA domain-containing protein 1; Cancer/testis antigen 46; CT46; Newborn ovary HORMA protein
Antigen Type: synthetic peptide
Antigen Type: HORMAD1 (HGNC:25245)
Gene ID: 84072
Primary Accession: Q86X24
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