HLA-H (I104) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3876
Background:
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined
Alternative Name:
Hereditary hemochromatosis protein, HLA-H, HFE, HLAH
Application Dilution: WB: 1:500~1:1000
Specificity: HLA-H (I104) polyclonal antibody detects endogenous levels of HLA-H protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 72-126 of Human HLA-H.
MW: ~ 40 kDa
Swis Prot.: Q30201
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined
Alternative Name:
Hereditary hemochromatosis protein, HLA-H, HFE, HLAH
Application Dilution: WB: 1:500~1:1000
Specificity: HLA-H (I104) polyclonal antibody detects endogenous levels of HLA-H protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 72-126 of Human HLA-H.
MW: ~ 40 kDa
Swis Prot.: Q30201
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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