HM13 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP14392b
Catalog Number: AC-AP14392b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34314
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34314
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene.
Other Names:
Minor histocompatibility antigen H13, 3423-, Intramembrane protease 1, IMP-1, IMPAS-1, hIMP1, Presenilin-like protein 3, Signal peptide peptidase, HM13, H13, IMP1, PSL3, SPP
Target/Specificity:
This HM13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human HM13.
Antigen Region:
325-354
Antigen Type: Synthetic Peptide
Gene Name: HM13
Gene ID: 81502
Primary Accession: Q8TCT9
NCBI Accession: NP_110416.1;NP_848695.1;NP_848696.1;NP_848697.1
Other Accession: NP_110416.1;NP_848697.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene.
Other Names:
Minor histocompatibility antigen H13, 3423-, Intramembrane protease 1, IMP-1, IMPAS-1, hIMP1, Presenilin-like protein 3, Signal peptide peptidase, HM13, H13, IMP1, PSL3, SPP
Target/Specificity:
This HM13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human HM13.
Antigen Region:
325-354
Antigen Type: Synthetic Peptide
Gene Name: HM13
Gene ID: 81502
Primary Accession: Q8TCT9
NCBI Accession: NP_110416.1;NP_848695.1;NP_848696.1;NP_848697.1
Other Accession: NP_110416.1;NP_848697.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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