HMBS polyclonal, anti-human, mouse

Background:
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Synonyms: PBG-D, PBGD, PORC, UPS

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human HMBS

Gene Symbol: HMBS

Gene ID: 3145

Swiss prot: P08397

Calculated MW: 39kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.