HMBS Polyclonal Antibody

Background:
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Area: Cancer, Cell Biology, Metabolism, Signal Transduction

Synonyms:
HMBS, PBG-D, PBGD, PORC, UPS

Immunogen: Recombinant fusion protein of human HMBS (NP_000181.2).

Swissprot: P08397
Gene ID: 3145

Calculated MW: 33 kDa/34 kDa/37 kDa/39 kDa
Observed MW: 45 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.