HMG-17 rabbit polyclonal, anti-human, mouse, rat

Backgroud: high mobility group nucleosomal binding domain 2(HMGN2) Homo sapiens The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014],function:Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation.,mass spectrometry: PubMed:10739259,PTM:Phosphorylation favors cytoplasmic localization.,similarity:Belongs to the HMGN family.,subcellular location:Cytoplasmic enrichment upon phosphorylation.,

Synonyms: HMGN2, HMG17, Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2

Gene Name: HMGN2

Gene ID: 3151

SwissProt ID: P05204

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.