HMG-2 Polyclonal Antibody

Background:
high mobility group box 2(HMGB2) Homo sapiens This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008],

Alternative Names:
HMGB2, HMG2, High mobility group protein B2, High mobility group protein 2, HMG-2

Immunogen: The antiserum was produced against synthesized peptide derived from human HMGB2. AA range:131-180

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 27

GeneID: HMGB2

Storage: -20°C/1 year

NOTE: For Research Use Only