HMG2 monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM2077a
Catalog Number: AC-AM2077a
Size: 100 µl
Isotype: mouse IgG2b
Clone Name: 523ct16.1.1
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgG2b
Clone Name: 523ct16.1.1
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC
Target/Specificity:
This HMG2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from human HMG2.
Antigen Region:
64-92
Antigen Type: Synthetic Peptide
Gene Name: HMGA2
Gene ID: 8091
Primary Accession: P52926
NCBI Accession: NP_003474.1;NP_003475.1
Other Accession: P52927; NP_003474.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC
Target/Specificity:
This HMG2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from human HMG2.
Antigen Region:
64-92
Antigen Type: Synthetic Peptide
Gene Name: HMGA2
Gene ID: 8091
Primary Accession: P52926
NCBI Accession: NP_003474.1;NP_003475.1
Other Accession: P52927; NP_003474.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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