HMG20A Polyclonal Antibody

Background:
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity).

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
HMG20A, HMGX1, HMGXB1

Immunogen: Recombinant fusion protein of human HMG20A (NP_060670.1).

Swissprot: Q9NP66
Gene ID: 10363

Calculated MW: 8 kDa/40 kDa
Observed MW: 41 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.