HMGA1 Polyclonal Antibody

Background:
This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Microbiology

Synonyms:
High mobility group (nonhistone chromosomal) protein isoforms I and Y, High mobility group AT hook 1, High mobility group AT-hook protein 1, High mobility group protein 1, High mobility group protein A1, High mobility group protein HMG-I/HMG-Y, High mobility group protein Ia, High mobility group protein R, HMG R, HMG-I(Y), HMGA1, HMGA1, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854, Nonhistone chromosomal high mobility group protein HMG I/HMG Y

Immunogen: Synthetic peptide of human HMGA1

Swissprot: P17096
Gene Accession: NP_665906

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-200, ELISA 1:2000-10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1564/sc-26348/sc-8982