HMGA2 antibody (clone 2D10), anti-human
€435.00
In stock
SKU
AC-AT2383a
Catalog Number: AC-AT2383a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT2383a">Request Information
Background:
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC
Antigen Type:
Recombinant Protein
Gene Name: HMGA2
Gene ID: 8091
NCBI Accession: NP_003474.1;NP_003475.1
Primary Accession: P52926
Other Accession: NM_003483
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC
Antigen Type:
Recombinant Protein
Gene Name: HMGA2
Gene ID: 8091
NCBI Accession: NP_003474.1;NP_003475.1
Primary Accession: P52926
Other Accession: NM_003483
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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