HMGA2 Polyclonal Antibody

Background:
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Developmental biology, Neuroscience, Stem cells

Synonyms:
HMGA2, BABL, HMGI-C, HMGIC, LIPO, STQTL9

Immunogen: A synthetic peptide of human HMGA2

Swissprot: P52926
Gene ID: 8091

Calculated MW: 9 kDa/10 kDa/11 kDa
Observed MW: 13 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.