HMGB1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7131
Background:
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Research suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture, including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, ATF-2, c-Jun and members of the NFκB family to activate transcription.
Alternative Name:
High mobility group protein B1, High mobility group protein 1, HMG-1, HMGB1, HMG1
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: HMGB1 polyclonal antibody detects endogenous levels of HMGB1 protein.
Immunogen:
Recombinant full length Human HMGB1.
MW: ~25 kDa
Swis Prot.: P09429
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Research suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture, including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, ATF-2, c-Jun and members of the NFκB family to activate transcription.
Alternative Name:
High mobility group protein B1, High mobility group protein 1, HMG-1, HMGB1, HMG1
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: HMGB1 polyclonal antibody detects endogenous levels of HMGB1 protein.
Immunogen:
Recombinant full length Human HMGB1.
MW: ~25 kDa
Swis Prot.: P09429
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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