HMGB1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Synonyms: HMG-1, HMG1, HMG3, SBP-1

Cellular Location: Cell membrane Chromosome Cytoplasm Endoplasmic reticulum-Golgi intermediate compartment Endosome Extracellular side Nucleus Peripheral membrane protein Secreted

Immunogen:
A synthetic peptide of human HMGB1

Gene Symbol: HMGB1

Gene ID: 3146

Swiss prot: P09429

Calculated MW: 25kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.