HMGB2 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP7195c
Background:
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Other Names:
High mobility group protein B2, High mobility group protein 2, HMG-2, HMGB2, HMG2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7195c was selected from the Center region of human HMGB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HMGB2
Gene ID: 3148
Primary Accession: P26583
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Other Names:
High mobility group protein B2, High mobility group protein 2, HMG-2, HMGB2, HMG2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7195c was selected from the Center region of human HMGB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HMGB2
Gene ID: 3148
Primary Accession: P26583
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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