HMGB2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Synonyms: HMG2

Immunogen:
A synthetic peptide of human HMGB2

Gene Symbol: HMGB2

Gene ID: 3148

Swiss prot: P26583

Calculated MW: 24kDa

Recommended dilution:
WB 1:2000-5000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.