HMGB2 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP7195c
Catalog Number: AC-AP7195c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18228
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18228
Applications: WB
Datasheet
Request Information
Background:
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Other Names:
High mobility group protein B2, High mobility group protein 2, HMG-2, HMGB2, HMG2
Target/Specificity:
This HMGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human HMGB2.
Antigen Region:
92-118
Antigen Type: Synthetic Peptide
Gene Name: HMGB2
Gene ID: 3148
Primary Accession: P26583
NCBI Accession: NP_001124160.1;NP_001124161.1;NP_002120.1
Other Accession: P52925; P17741; P40673
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Other Names:
High mobility group protein B2, High mobility group protein 2, HMG-2, HMGB2, HMG2
Target/Specificity:
This HMGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human HMGB2.
Antigen Region:
92-118
Antigen Type: Synthetic Peptide
Gene Name: HMGB2
Gene ID: 3148
Primary Accession: P26583
NCBI Accession: NP_001124160.1;NP_001124161.1;NP_002120.1
Other Accession: P52925; P17741; P40673
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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