HMGCL polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Name:
HL, HMG-CoA lyase

Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Specificity: HMGCL polyclonal antibody detects endogenous levels of HMGCL protein.

Immunogen:
Recombinant protein of human HMGCL.

MW: ~ 34 kDa

Swis Prot.: P35914

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.