HMGCL Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
HMGCL, HL

Immunogen: Recombinant fusion protein of human HMGCL (NP_000182.2).

Swissprot: P35914
Gene ID: 3155

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.