HMGCS2 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial), 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2, 3 hydroxy 3 methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, HMCS2, HMG CoA synthase, HMG-CoA synthase, HMGCS 2, HMGCS2, Hydroxymethylglutaryl CoA synthase, Hydroxymethylglutaryl CoA synthase mitochondrial, Hydroxymethylglutaryl-CoA synthase, mitochondrial

Immunogen: Synthetic peptide of human HMGCS2

Swissprot: P54868
Gene Accession: NP_005509

Calculated MW: 57 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-32425/sc-32426/sc-32424/sc-33828