HMGCS2 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
HMGCS2

Immunogen: Recombinant fusion protein of human HMGCS2 (NP_005509.1).

Swissprot: P54868
Gene ID: 3158

Calculated MW: 50 kDa/52 kDa/56 kDa
Observed MW: 50 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.