HNF1A polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: HNF1, LFB1, TCF1, MODY3, TCF-1, HNF-1A, IDDM20

Cellular Location: Nucleus

Immunogen:
A synthetic peptide of human HNF1A

Gene Symbol: HNF1A

Gene ID: 6927

Swiss prot: P20823

Calculated MW: 67kDa

Recommended dilution:
WB 1:500-2000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.