HNF1A Polyclonal Antibody

Background:
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
HNF1A, HNF-1A, HNF1, IDDM20, LFB1, MODY3, TCF-1, TCF1

Immunogen: A synthetic peptide of human HNF1A

Swissprot: P20823
Gene ID: 6927

Calculated MW: 12 kDa/27 kDa/30 kDa/43 kDa/55-70 kDa
Observed MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.