HNMT monoclonal, anti-human
€0.00
In stock
SKU
AC-AM2023b
Catalog Number: AC-AM2023b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 432CT31.4.2
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 432CT31.4.2
Applications: WB
Datasheet
Request Information
Background:
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Other Names:
Histamine N-methyltransferase, HMT, HNMT
Target/Specificity:
Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: HNMT
Gene ID: 3176
Primary Accession: P50135
NCBI Accession: NP_001019245.1;NP_001019246.1;NP_008826.1
Other Accession: NP_008826.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Other Names:
Histamine N-methyltransferase, HMT, HNMT
Target/Specificity:
Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: HNMT
Gene ID: 3176
Primary Accession: P50135
NCBI Accession: NP_001019245.1;NP_001019246.1;NP_008826.1
Other Accession: NP_008826.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review