HNMT monoclonal(Ascites), anti-human

Background:
In mammals, histamine is metabolized by two majorpathways: N(tau)-methylation via histamine N-methyltransferase andoxidative deamination via diamine oxidase. This gene encodes thefirst enzyme which is found in the cytosol and usesS-adenosyl-L-methionine as the methyl donor. In the mammalianbrain, the neurotransmitter activity of histamine is controlled byN(tau)-methylation as diamine oxidase is not found in the centralnervous system. A common genetic polymorphism affects the activitylevels of this gene product in red blood cells. Multiplealternatively spliced transcript variants that encode differentproteins have been found for this gene.

Other Names:
Histamine N-methyltransferase, HMT, HNMT

Target/Specificity:
Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody.

Antigen Type: Recombinant Protein

Gene Name: HNMT
Gene ID: 3176
Primary Accession: P50135
NCBI Accession: NP_001019245.1;NP_001019246.1;NP_008826.1
Other Accession: NP_008826.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.