HNMT polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7371
Background:
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
Alternative Name:
Histamine N methyltransferase, Histamine N-methyltransferase, HMT, HNMT, HNMT S1, HNMT S2, HNMT_HUMAN,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:20 - 1:50
Specificity: HNMT polyclonal antibody detects endogenous levels of HNMT protein.
Immunogen:
Recombinant full length Human HNMT.
MW: ~33 kDa
Swis Prot.: P50135
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
Alternative Name:
Histamine N methyltransferase, Histamine N-methyltransferase, HMT, HNMT, HNMT S1, HNMT S2, HNMT_HUMAN,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:20 - 1:50
Specificity: HNMT polyclonal antibody detects endogenous levels of HNMT protein.
Immunogen:
Recombinant full length Human HNMT.
MW: ~33 kDa
Swis Prot.: P50135
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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