HNMT polyclonal, anti-human, mouse

Background:
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Synonyms: HMT, HNMT-S1, HNMT-S2, MRT51

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human HNMT

Gene Symbol: HNMT

Gene ID: 3176

Swiss prot: P50135

Calculated MW: 33kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100, IP 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.