hNRG1-Q212 polyclonal, anti-human
€0.00
In stock
SKU
AC-AP20633a
Catalog Number: AC-AP20633a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01275
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01275
Applications: WB
Datasheet
Request Information
Background:
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
Other Names:
Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, Neuregulin-1, Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-derived factor, NRG1, GGF, HGL, HRGA, NDF, SMDF
Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.
Gene Name: NRG1
Gene ID: 3084
Primary Accession: Q02297
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
Other Names:
Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, Neuregulin-1, Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-derived factor, NRG1, GGF, HGL, HRGA, NDF, SMDF
Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.
Gene Name: NRG1
Gene ID: 3084
Primary Accession: Q02297
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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