hnRNP E1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70555
Background:
hnRNP E1 is a member of the hnRNP family of proteins that are involved in pre-mRNA processing and mRNA export, localization, stability, and translation (1-6). hnRNP E1 exerts a wide range of biological functions, such as transcriptional activation of mouse MOR gene expression (7), attenuation of alternative splicing of GHR pseudoexon expression (8), stabilization of collagen I and II (9), beta-globin (10), and androgen receptor (11) mRNAs, and regulation of translation of various genes including Dab2, ILEI, and Bag-1 (12,13). hnRNP E1 is ubiquitously expressed. Phosphorylation of hnRNP E1 affects its RNA binding affinity (13,14).
Alternative Name:
PCBP1,HNRPE1,HNRPX,hnRNP-E1,hnRNP-X ,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: hnRNP E1 polyclonal antibody detects endogenous levels of hnRNP E1 protein.
Immunogen:
A synthetic peptide of human PCBP1.
MW: ~ 37 kDa
Swis Prot.: Q15365
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
hnRNP E1 is a member of the hnRNP family of proteins that are involved in pre-mRNA processing and mRNA export, localization, stability, and translation (1-6). hnRNP E1 exerts a wide range of biological functions, such as transcriptional activation of mouse MOR gene expression (7), attenuation of alternative splicing of GHR pseudoexon expression (8), stabilization of collagen I and II (9), beta-globin (10), and androgen receptor (11) mRNAs, and regulation of translation of various genes including Dab2, ILEI, and Bag-1 (12,13). hnRNP E1 is ubiquitously expressed. Phosphorylation of hnRNP E1 affects its RNA binding affinity (13,14).
Alternative Name:
PCBP1,HNRPE1,HNRPX,hnRNP-E1,hnRNP-X ,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: hnRNP E1 polyclonal antibody detects endogenous levels of hnRNP E1 protein.
Immunogen:
A synthetic peptide of human PCBP1.
MW: ~ 37 kDa
Swis Prot.: Q15365
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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