HNRNPD polyclonal, anti-human, mouse, rat

Background:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.

Synonyms: AUF1, AUF1A, HNRPD, P37, hnRNPD0

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human HNRNPD

Gene Symbol: HNRNPD

Gene ID: 3184

Swiss prot: Q14103

Calculated MW: 38kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.