HNRNPH3 polyclonal (Center), anti-human

HNRNPH3 polyclonal (Center), anti-human

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In stock
SKU
AC-AP17082c
Catalog Number: AC-AP17082c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36996
Applications: WB
Datasheet

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Background:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized.

Other Names:
Heterogeneous nuclear ribonucleoprotein H3, hnRNP H3, Heterogeneous nuclear ribonucleoprotein 2H9, hnRNP 2H9, HNRNPH3, HNRPH3

Target/Specificity:
This HNRNPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the Central region of human HNRNPH3.

Antigen Region:
90-117

Antigen Type: Synthetic Peptide

Gene Name: HNRNPH3
Gene ID: 3189
Primary Accession: P31942
NCBI Accession: NP_036339.1;NP_067676.2
Other Accession: NP_036339.1;NP_067676.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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