HNRNPLL polyclonal, anti-human
€305.00
In stock
SKU
BS61667
Background:
Heterogeneous nuclear ribonucleoprotein L-like (hnRNP LL) is a nuclear RNA-binding protein that shares 69% amino acid homology with hnRNP L, a component of the hnRNP complex that regulates mRNA formation, packaging, and processing. hnRNP LL is induced in activated T cells and functions as a critical regulator of alternative splicing of CD45, a tyrosine phosphatase crucial for T cell development and activation. hnRNP LL also regulates the splicing of CD44 and Stat5a. The four isoforms of hnRNP LL are generated by alternative splicing and are widely expressed in human tissues.
Alternative Name:
Heterogeneous nuclear ribonucleoprotein L-like, hnRNPLL, Stromal RNA-regulating factor, HNRNPLL, HNRPLL, SRRF, BLOCK24
Application Dilution: WB: 1:500~1:1000
Specificity: HNRPLL polyclonal antibody detects endogenous levels of HNRPLL protein.
Immunogen:
Synthetic peptide, corresponding Human HNRPLL.
MW: ~ 60 kDa
Swis Prot.: Q8WVV9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Heterogeneous nuclear ribonucleoprotein L-like (hnRNP LL) is a nuclear RNA-binding protein that shares 69% amino acid homology with hnRNP L, a component of the hnRNP complex that regulates mRNA formation, packaging, and processing. hnRNP LL is induced in activated T cells and functions as a critical regulator of alternative splicing of CD45, a tyrosine phosphatase crucial for T cell development and activation. hnRNP LL also regulates the splicing of CD44 and Stat5a. The four isoforms of hnRNP LL are generated by alternative splicing and are widely expressed in human tissues.
Alternative Name:
Heterogeneous nuclear ribonucleoprotein L-like, hnRNPLL, Stromal RNA-regulating factor, HNRNPLL, HNRPLL, SRRF, BLOCK24
Application Dilution: WB: 1:500~1:1000
Specificity: HNRPLL polyclonal antibody detects endogenous levels of HNRPLL protein.
Immunogen:
Synthetic peptide, corresponding Human HNRPLL.
MW: ~ 60 kDa
Swis Prot.: Q8WVV9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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