HNRNPM polyclonal (N-term), anti-human

HNRNPM polyclonal (N-term), anti-human

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In stock
SKU
AC-AP14009a
Catalog Number: AC-AP14009a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33926
Applications: WB, IHC-P
Datasheet

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Background:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.

Other Names:
Heterogeneous nuclear ribonucleoprotein M, hnRNP M, HNRNPM, HNRPM, NAGR1

Target/Specificity:
This HNRNPM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HNRNPM.

Antigen Region:
21-50

Antigen Type: Synthetic Peptide

Gene Name: HNRNPM
Gene ID: 4670
Primary Accession: P52272
NCBI Accession: NP_005959.2;NP_112480.2
Other Accession: NP_112480.2;NP_005959.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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