Hox-A1 polyclonal, anti-human
€388.00
In stock
SKU
BS71906
Background:
Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves.
Alternative Name:
Homeobox protein Hox-A1, Homeobox protein Hox-1F, HOXA1, HOX1F
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: Hox-A1 polyclonal antibody detects endogenous levels of Hox-A1 protein.
Immunogen:
Recombinant protein of human HOXA1
MW: 64kDa
Swis Prot.: P49639
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves.
Alternative Name:
Homeobox protein Hox-A1, Homeobox protein Hox-1F, HOXA1, HOX1F
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: Hox-A1 polyclonal antibody detects endogenous levels of Hox-A1 protein.
Immunogen:
Recombinant protein of human HOXA1
MW: 64kDa
Swis Prot.: P49639
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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