Hox-A7 polyclonal antibody, anti-human, mouse, rat

Background:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA7 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis and differentiation. For example, Homeobox protein Hox-A7 represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. HOXA7 is highly similar to the antennapedia (Antp) gene of Drosophila.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: HOXA7, HOX1A, Homeobox protein Hox-A7, Homeobox protein Hox 1.1, Homeobox protein Hox-1A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year