Hox C13 polyclonal, anti-human, mouse

Quantity: 25 µl

Background:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.

Synonyms:
HOXC13, HOX3, ECTD9, HOX3G

Isotype: Guinea pig Polyclonal (Hox C13-2.1)

Immunogen:
Synthetic human Hox C13 peptide (PEPSGALPGDDLS-C), conjugated to KLH

Form: Stabilized Serum

Specificity:
Specific for human Hox C13, localized in nuclei of hair matrix cells, including cells of dermal papilla lining and lower cortex.

Reactivity: human, mouse

Applications: Immunohistochemistry on frozen sections, Immunoblotting (western, ECL)

Working DIlution: 1: 100 for immunohistochemistry 1:2,000 for Western blotting (ECL)

Storage: 2-8C

References:
- Jave-Suarez LF. Et al. (2002) J Biol Chem 277: 3718-3726
- Cribier B. et al. (2004) J Invest Dermatol 122: 1078-1083